pentobarbital increases results of ifosfamide by affecting hepatic enzyme CYP2B6 metabolism. Use Caution/Watch. Coadministration of ifosfamide with CYP2B6 inducers may well improve metabolism of ifosfamide to its metabolite. Observe for greater effects/toxicities if combined with CYP2B6 inducers.
pentobarbital will reduce the extent or effect of dutasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.
pentobarbital will lower the extent or result of midazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will minimize the extent or impact of zaleplon by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unfamiliar.
pentobarbital will reduce the level or result of paclitaxel protein bound by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unknown.
pentobarbital will lessen the level or impact of buspirone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
Caution when discontinuing CYP3A4 inducers that happen to be coadministered with hydrocodone; plasma concentrations of hydrocodone may well boost and may lead to perhaps fatal respiratory depression
With therapeutic doses of TCAs, barbiturates boost metabolism and reduce blood concentrations of TCAs.
pentobarbital will lessen the level or impact of alosetron by influencing hepatic enzyme CYP2C9/10 metabolism. Small/Importance Mysterious.
pentobarbital will minimize the level nembutal mexico or impact of montelukast by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unidentified.
pentobarbital will decrease the extent or effect of mavacamten by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will minimize the extent or result of norgestrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Moderate CYP3A4 inducers may perhaps minimize progestin concentration; take into account usage of additional barrier approaches
pentobarbital will lessen the extent or result of finasteride by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Mysterious.
pentobarbital will reduce the extent or outcome of irinotecan liposomal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.